MBBS FRCP FRCPCH DRCOG MD
Helen qualified at Barts and the London Hospital (1981, MBBS) and completed paediatric endocrinology training and her doctorate in London (1995-1996).
Her interests are in the endocrine effects of childhood brain tumours and their treatment, having set up the first UK neuroendocrine rehabilitative service for brain tumour survivors, and a national advisory group for pituitary tumours (HPAT). She also chairs the UK National Project Board for the development of evidence-based management guidelines of rare paediatric endocrine tumours. She additionally spends her time advocating for brain tumour survivors via All-Party Parliamentary Groups and the Success Charity, which she founded. She loves music and plays the piano, sings and dances the tango.
- Neuroendocrine effects of childhood cancer/ brain tumours
- Acquired hypopituitarism
- Abnormalities of growth and development
Research & Academic Interests
Helen's research interests focus on the topics of hormone secretion, growth, puberty and fertility status after cancer therapies. Her doctorate examined the neuroendocrine disturbances seen during and after different therapies for childhood brain tumours.
She is a member of the European Society of Paediatric Oncology (SIOP-E) and the UK Children's Cancer and Leukaemia Group (CCLG), where she works with professionals from other specialties to improve quality of survival of children with brain tumours.
Howard SR, Freeson S, Harrison B, Izatt L, Natu S, Newbold K, Pomplun S, Spoudeas HA, Wilne S, Kurzawinski TR, Gaze MN. Paediatric differentiated thyroid carcinoma: a UK National Clinical Practice Consensus Guideline. Endocrine Related Cancer 2022; ERC-22-0035. doi: 10.1530/ERC-22-0035.
Picariello S, Cerbone M, D'Arco F, Gan HW, O-Hare P, Aquilina K, Opocher E, Hargrave D, Spoudeas HA. A 40-year cohort study of evolving hypothalamic dysfunction in infants and young children (<3 years) with optic pathway gliomas. Cancers (Basel) 2022; 14(3):747. doi: 10.3390/cancers1403747.
van Iersel L, Mulder RL, Denzer C, Cohen LE, Spoudeas HA, ... van Santen HM. Hypothalamo-pituitary and other endocrine surveillance among childhood cancer survivors. Endocrine Reviews 2021;bnab040. doi: 10.1210/endrev/bnab040.
Cerbone M, Visser J, Bulwer C, Ederies A, Vallabhaneni K, Ball S, Kamaly-Asl I, Grossman A, Gleeson H, Korbonits M, Nanduri V, Tziaferi V, Jacques T, Spoudeas HA. Management of children and young people with idiopathic pituitary stalk thickening, central diabetes insipidus, or both: a national clinical practice consensus guideline. Lancer Child & Adolescent Health 2021; 5(9):662-676. doi: 10.1016/S2352-4642(21)00088-2.
Wagner AP, Carroll C, White SR, Watson P, Spoudeas HA, Hawkins MM, Walker DA, Clare ICH, Holland AJ, Ring H. Long-term cognitive outcome in adult survivors of an early childhood posterior fossa brain tumour. International Journal of Clinical Oncology 2020; 25(10):1763-1773. doi: 10.1007/s10147-020-01725-7.