Research and Innovation

Inflammatory syndrome in children is not caused by a special strain of coronavirus

The world’s first genetic study of coronavirus from children with inflammatory syndrome PIMS-TS, led by researchers at the UCL Great Ormond Street Institute of Child Health (ICH), suggests characteristics of the human host, rather than of the virus itself, are likely to make children more susceptible to the syndrome.

GOSH celebrates one year anniversary of the opening of the Zayed Centre for Research into Rare Diseases in Children

It’s been a year since the Zayed Centre for Research opened its doors to patients, clinicians and researchers from across Great Ormond Street Hospital (GOSH) and UCL, and to celebrate we’re taking a look back at its work and achievements.

Researchers grow functioning blood vessels from scratch

Human cells ‘sent back in time’ to behave as they did in the womb can be used to grow networks of blood vessels in the laboratory, according to research by an international team including the UCL Great Ormond Street Institute of Child Health (ICH). The findings mark a significant step forward in engineering tissue and organs to study disease, test treatments or, in the future, offer rejection-free transplants for children with organ failure.

Lab-grown mini-organs could offer treatment hope for children with intestinal failure

Pioneering scientists at Great Ormond Street Hospital (GOSH), the UCL Great Ormond Street Institute of Child Health (ICH) and the Francis Crick Institute have grown human intestinal grafts using stem cells from patient tissue that could one day lead to personalised transplants for children with intestinal failure, according to a study published in Nature Medicine.