Research and Innovation

Researchers grow functioning blood vessels from scratch

Human cells ‘sent back in time’ to behave as they did in the womb can be used to grow networks of blood vessels in the laboratory, according to research by an international team including the UCL Great Ormond Street Institute of Child Health (ICH). The findings mark a significant step forward in engineering tissue and organs to study disease, test treatments or, in the future, offer rejection-free transplants for children with organ failure.

Lab-grown mini-organs could offer treatment hope for children with intestinal failure

Pioneering scientists at Great Ormond Street Hospital (GOSH), the UCL Great Ormond Street Institute of Child Health (ICH) and the Francis Crick Institute have grown human intestinal grafts using stem cells from patient tissue that could one day lead to personalised transplants for children with intestinal failure, according to a study published in Nature Medicine.

ICH researchers develop a technique to 'print' healthy new tissue

A pioneering international study led by the UCL Great Ormond Street Institute of Child Health (ICH) has seen researchers develop a photosensitive bio-gel that uses light treatment to ‘print’ healthy new tissue directly into specific tissues and organs, and sustain blood supply that would allow it to thrive, according to results published in the Nature Biomedical Engineering journal today (22nd June).

Genetic study of over 1,000 people sheds new light on immune-system disorders

Whole Genome Sequencing (WGS) can provide a more accurate diagnosis for patients with missing or poorly functioning immune systems, while providing new insight into complex genetic causes, according to results of a new international study involving researchers from the UCL Great Ormond Street Institute of Child Health (ICH).

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