Clinical guidelines

Clinical guidelines are used by the health professionals at Great Ormond Street Hospital for a wide range of conditions, treatments and tests.

Search below for clinical guidelines, or filter by speciality.

Clinical guidelines

Search for clinical guidelines

Invasive monitoring (IM) and Stereo-electroencephalography (SEEG) for epilepsy surgery: nursing management

This guideline is intended to guide and facilitate the care of patients under the care of the clinical teams at Great Ormond Street Hospital for Children NHS Trust (GOSH). The guidance contained herein is not intended to replace individual assessment and personalised treatment of the patient.

Refeeding guidelines for children and young people with feeding and eating disorders admitted to the Mildred Creak Unit at Great Ormond Street Hospital

Clinical guideline from Great Ormond Street Hospital for the recognition, prevention and treatment of the refeeding syndrome in children and young people admitted in the Department of Child and Adolescent Mental Health who have experienced recent starvation. 

Coagulation factors

Coagulation factors are proteins, which in the blood, cause clotting. The factors are manufactured either from human blood (plasma derived) or genetic engineering (recombinant). Advice should be sought from a Consultant Haematologist prior to any decision to prescribe and administer coagulation factors.

Ketogenic diet

The ketogenic diet (KD) is a therapeutic diet, which has been shown to improve seizure control in patients with drug resistant epilepsy, and is used in some patients with metabolic conditions for example, glucose transporter type 1 deficiency syndrome (GLUT1) and pyruvate dehydrogenase deficiency (PDH).

NOTE: We review our guidelines regularly and this guideline is now past its review date. The content of the guideline below may not reflect the most recent evidence based practice. Please use with caution.