Conditions we treat

Use the search box below to learn more about the conditions we treat at Great Ormond Street Hospital. 

Alternating hemiplegia

Alternating hemiplegia is a rare condition where a child has episodes of weakness affecting one side of the body. This weakness can affect all the muscles on the affected side, not just those in the limbs. After an episode, the weakness improves, but will recur during the next episode.

Anal fissure

Anal fissures are tiny tears in the skin around the anus and can be painful. They usually develop as a side effect of constipation. Constipation is the condition where a person passes faeces (poo) less frequently than usual and the poo is harder, drier and painful to pass.

Anorectal anomaly

An anorectal anomaly is a disorder affecting the anus and the rectum, the last part of the digestive system.This page explains about anorectal anomaly, how it can be treated and what to expect when a child comes to Great Ormond Street Hospital (GOSH).

Antley-Bixler syndrome

This page from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of Antley-Bixler syndrome and where to get help. Antley-Bixler syndrome is a type of complex craniosynostosis named after the doctors who first described it.

Aortic arch obstruction

Our Cardiorespiratory Unit regularly refers to information published by the British Heart Foundation (BHF) when explaining aortic arch obstruction to our patients and their families. More information on aortic arch obstruction can be found in their coarctation of the aorta factsheet.

Aortic regurgitation

Aortic regurgitation occurs when the aortic valve (linking the left ventricle to the aorta) does not close properly when the heart contracts. This means blood leaks back into the left ventricle, which then has to work harder to pump the extra blood away from the heart to the rest of the body. This can lead to the enlargement and thickening of the ventricle wall.

Aortic valve stenosis

The aortic valve is a one-way valve between the left pumping chamber (ventricle) of the heart and the major blood vessel taking blood to the body (aorta). Aortic stenosis (AS) describes a condition where the aortic valve is smaller or tighter than it should be.

Apert syndrome

Apert syndrome is a type of complex craniosynostosis named after the doctor who first described it in the early 20th century. This information sheet from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of Apert syndrome and where to get help.

Aplastic anaemia

Aplastic anaemia is a serious condition affecting the blood, where the bone marrow and stem cells do not produce enough blood cells. It is also called bone marrow failure and can happen suddenly (acute) or develop over a period of time (chronic). This page explains about aplastic anaemia, how it is treated and what to expect when a child comes to Great Ormond Street Hospital (GOSH) for treatment. 

Arrhythmias

Arrhythmias are abnormal heart rhythms, which can prevent the heart pumping efficiently. This page from Great Ormond Street Hospital (GOSH) explains how the heart beats normally, what happens when it starts to beat abnormally and how it can be treated.