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Administration of Non-Cytotoxic Medication via an Intracerebroventricular Reservoir

The purpose of this document is to provide guidance for the administration of non-cytotoxic injection or infusion via an Intracerebroventricular (ICV) reservoir at Great Ormond Street Hospital (GOSH). 

This guideline is to be used for the administration of cerliponase alfa/BMN190 and may need to be adapted for administration of other ICV medications. 

For intrathecal or ICV administration of cytotoxic drugs please see the clinical guideline; Intrathecal cytotoxic chemotherapy: administration via a lumbar puncture or Ommaya reservoir.

Refeeding guidelines for children and young people with feeding and eating disorders admitted to the Mildred Creak Unit at Great Ormond Street Hospital

Clinical guideline from Great Ormond Street Hospital for the recognition, prevention and treatment of the refeeding syndrome in children and young people admitted in the Department of Child and Adolescent Mental Health who have experienced recent starvation.