Intrathecal methotrexate is a chemotherapy drug which is given to prevent leukaemia cells entering the cerebrospinal fluid (CSF) around the spine and brain. This drug is also used to treat leukaemia found in the CSF. This page from Great Ormond Street Hospital (GOSH) describes intrathecal methotrexate, how it is given and some of the possible side effects.
Opsoclonus myoclonus syndrome (OMS), also known as dancing eye syndrome (DES) or Kinsbourne syndrome, is a rare neurological condition which develops over days or weeks in early childhood. This information sheet from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of opsoclonus myoclonus syndrome and where to get help.
The purpose of this guideline is to provide guidance about specimen collection at Great Ormond Street Hospital (GOSH).
NOTE: We review our guidelines regularly and this guideline is now past its review date. The content of the guideline below may not reflect the most recent evidence based practice. Please use with caution.
When young people are told that they have a diagnosis of multiple sclerosis (MS) they usually have lots of questions. Some young people may have never heard of the condition and most will never have met anybody else who has this condition. It can be difficult to know where to look for information and how to find answers to their questions.