This booklet has been produced by the PID UK Medical Advisory Panel and Patient Representative Panel in conjunction with Great Ormond Street Hospital and the Great North Children’s Hospital. It provides information on immunoglobulin therapy (Ig therapy) to help answer the questions parents may have about this form of treatment for children and young people affected by primary immunodeficiency (PID).The information should not, however, replace advice from a clinical immunologist.
Potassium iodate is a thyroid blocking medicine. It is given before a particular type of isotope scan at Great Ormond Street Hospital (GOSH) called a MIBG scan. The potassium iodate protects the thyroid against the isotope given during this scan.
The skin is complex with an array of functions. It is the body’s largest organ, protecting the deeper tissues and organs from mechanical damage, chemical damage, bacterial damage, ultraviolet radiation and thermal damage. The skin aids in regulating body temperature, in excretion of urea and uric acid and also synthesis of vitamin D (Marieb 2012).
A technique for replacing oesophageal tissue in babies who have not developed the organ properly is currently being established by surgeons at Great Ormond Street Hospital, in collaboration with teams from UCL (University College London) and Royal Free Hospital.
Iloprost is known as a prostaglandin. It acts by imitating a naturally occurring substance in the body called prostacyclin. It is prescribed at GOSH to treat pulmonary hypertension (high blood pressure in the blood vessels in the lungs). It works by lowering blood pressure by widening the blood vessels in the lungs.
Sirolimus (also known as rapamycin) is an immunosuppressant medicine used at Great Ormond Street Hospital (GOSH), which damps down the immune system. It is most commonly used following kidney transplant to prevent the new kidney being rejected by the body. However it is now being used for other medical conditions.
Changes in the way working genes are delivered to children with SCID (Severe Combined Immunodeficiency) could make gene therapy for the disease even safer, finds research led by a team at Great Ormond Street Hospital (GOSH) and its research partner the UCL Institute of Child Health
This guideline covers the recognition, management and prevention of infiltration and extravasation injury.
NOTE: We review our guidelines regularly and this guideline is now past its review date. The content of the guideline below may not reflect the most recent evidence based practice. Please use with caution.
Tracheal resection is an operation on the windpipe – the tube which connects the voicebox to the lungs. It involves a short section of the windpipe being removed and the cut ends of the windpipe are stitched back together.
Tendon sheath injections are suggested when the tissues around a tendon are painful, swollen or difficult to move. Tendon sheath injections on their own are unlikely to offer a cure, but can be helpful alongside other treatments such as physiotherapy, splinting and other longer term medicines.
Propranolol belongs to a group of drugs called beta blockers. It is used in patients with heart problems to control high blood pressure or irregular heart beats. It is also used to treat certain types of vascular birthmarks. It is also used to prevent migraines and headaches.
Head injuries may involve the scalp, the skull, the brain or its protective membranes.This page from Great Ormond Street Hospital (GOSH) explains the effects that a head injury can have on a child. It also sets out the treatment and care of any complications following a head injury.