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Intrathecal methotrexate

Intrathecal methotrexate is a chemotherapy drug which is given to prevent leukaemia cells entering the cerebrospinal fluid (CSF) around the spine and brain. This drug is also used to treat leukaemia found in the CSF. This page from Great Ormond Street Hospital (GOSH) describes intrathecal methotrexate, how it is given and some of the possible side effects.

Parry-Romburg syndrome

Parry-Romburg syndrome (also known as Progressive Hemifacial Atrophy) is a rare condition affecting the skin and soft tissues on one side of the face (hemifacial). This information sheet from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of Parry-Romburg syndrome and where to get help.

Mouth care

The purpose of this guideline is to provide guidance about mouth care at Great Ormond Street Hospital (GOSH).

NOTE: We review our guidelines regularly and this guideline is now past its review date. The content of the guideline below may not reflect the most recent evidence based practice. Please use with caution.