Mercaptamine is a medicine that stops the build up of an amino acid called cystine in the body. Large amounts of cystine can build up in the body causing damage to tissues and organs when a child has a condition called cystinosis. Mercaptamine eye drops are prescribed to reduce build up of cystine crystals in the eyes.
Pharmacy is defined as the study of medicines. It involves studying how medicines are discovered, developed and made. It also covers how medicines work in the body to prevent or treat disease, and how active ingredients can be made in to medicines.
Rituximab (brand name MabThera®) is a relatively new medicine which works on the immune system. It removes some of the white blood cells in the body which are called B cells. Removing these stops the production of antibodies that may play a role in your child’s illness.
The first children to receive a genetic diagnosis through the 100,000 Genomes Project have been given their results at Great Ormond Street Hospital (GOSH), part of the North Thames Genomic Medical Centre (NTGMC.)
A gastrostomy is a surgical opening through the abdomen into the stomach. A feeding device is inserted through this opening. This allows your child to be fed directly into their stomach, bypassing the mouth and throat.
A gastrostomy is a feeding tube that is inserted directly into the stomach either surgically under direct vision (open or laproscopic), endoscopically (with a camera), or radiologically (x-ray guidance). A gastrostomy tube allows the delivery of supplemental nutrition and medications directly into the stomach. It also provides a mechanism to drain gastric contents if required. In order for gastrostomy feeding to be successful the child or young person must have a functioning gastrointestinal tract.
The purpose of this guideline is to provide guidance in the use of arterial lines at Great Ormond Street Hospital (GOSH).
NOTE: We review our guidelines regularly and this guideline is now past its review date. The content of the guideline below may not reflect the most recent evidence based practice. Please use with caution.
Glomerulonephritis is the term used when the glomeruli become inflamed. This means that the blood is less able to pass through the blood vessels in the glomerulus and so the kidneys cannot make as much urine as usual.
The anaesthetic team consists of a consultant (or specialist) anaesthetist, sometimes assisted by a junior anaesthetist, and an anaesthetic assistant, usually a nurse. An anaesthetist is a doctor who makes your child go to sleep and stay pain-free during an operation. They will stay with your child for the whole operation.
Bronchiolitis is a common type of chest infection that tends to affect babies and young children under a year old. Although many bronchiolitis infections get better without treatment, a small number of children will need treatment in hospital, occasionally in the intensive care unit.This information sheet from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of bronchiolitis and where to get help.
The symptoms of a 15-year-old girl with a rare disorder improved dramatically after just one day of treatment with the B vitamins biotin and thiamine administered by Great Ormond Street Hospital (GOSH).