Mercaptamine is a medicine that stops build up of an amino acid called cystine in the body. Large amounts of cystine can build up in the body causing damage to tissues and organs when a child has a condition called cystinosis. Mercaptamine eye drops are prescribed to reduce build up of cystine crystals in the eyes.
The first children to receive a genetic diagnosis through the 100,000 Genomes Project have been given their results at Great Ormond Street Hospital (GOSH), part of the North Thames Genomic Medical Centre (NTGMC.)
Rituximab (brand name MabThera®) is a relatively new medicine which works on the immune system. It removes some of the white blood cells in the body which are called B cells. Removing these stops the production of antibodies that may play a role in your child’s illness.
A gastrostomy is a feeding tube that is inserted directly into the stomach either surgically under direct vision (open or laproscopic), endoscopically (with a camera), or radiologically (x-ray guidance). A gastrostomy tube allows the delivery of supplemental nutrition and medications directly into the stomach. It also provides a mechanism to drain gastric contents if required. In order for gastrostomy feeding to be successful the child or young person must have a functioning gastrointestinal tract.
Pharmacy is defined as the study of medicines. It involves studying how medicines are discovered, developed and made. It also covers how medicines work in the body to prevent or treat disease, and how active ingredients can be made in to medicines.
A gastrostomy is a surgical opening through the abdomen into the stomach. A feeding device is inserted through this opening. This allows your child to be fed directly into their stomach, bypassing the mouth and throat.
The purpose of this guideline is to provide guidance about the glomerular filtration rate measurement: IohexolTM method at Great Ormond Street Hospital.
NOTE: We review our guidelines regularly and this guideline is now past its review date. The content of the guideline below may not reflect the most recent evidence based practice. Please use with caution.
The anaesthetic team consists of a consultant (or specialist) anaesthetist, sometimes assisted by a junior anaesthetist, and an anaesthetic assistant, usually a nurse. An anaesthetist is a doctor who makes your child go to sleep and stay pain-free during an operation. They will stay with your child for the whole operation.
A syndrome is a collection of signs that are often seen together. Sturge-Weber syndrome (SWS) is a condition affecting the skin, brain and eyes. It is named after the doctors who described it in the late 19th century and early 20th century.
When young people are told that they have a diagnosis of multiple sclerosis (MS) they usually have lots of questions. Some young people may have never heard of the condition and most will never have met anybody else who has this condition. It can be difficult to know where to look for information and how to find answers to their questions.
Find out more about cortisol deficiency and how it is treated. This page also contains information from Great Ormond Street Hospital (GOSH) about how to deal with illnesses, accidents and other stressful events in children on cortisol replacement.
The symptoms of a 15-year-old girl with a rare disorder improved dramatically after just one day of treatment with the B vitamins biotin and thiamine administered by Great Ormond Street Hospital (GOSH).
This information from Great Ormond Street Hospital (GOSH) explains about junctional epidermolysis bullosa generalised intermediate type and how it can be managed. It also contains suggestions for making everyday life more comfortable.