This guideline is intended to guide and facilitate the care of patients under the care of the clinical teams at Great Ormond Street Hospital for Children NHS Trust (GOSH). It has been approved by the Guideline Approval Group and is for use by staff of all disciplines and levels in these health care teams. The guidance contained here in is not intended to replace individual assessment and personalised treatment of the patient.
NOTE: We review our guidelines regularly and this guideline is now past its review date. The content of the guideline below may not reflect the most recent evidence based practice. Please use with caution.
Landau Kleffner syndrome (LKS) is a rare epilepsy. It occurs in children usually between the ages of three and nine years and is characterised by loss of language skills and silent electrical seizures during sleep. It may be associated with convulsive seizures and additional difficulties with behaviour, social interaction, motor skills and learning. It is not usually life-threatening, but can impact greatly on quality of life unless it responds well to treatment. It occurs in approximately one child in a million. The disease is more common in boys and does not usually run in families.