The brain uses a tremendous amount of oxygen in order to function. When the amount of oxygen that is available to the brain is temporarily reduced, we know that vulnerable brain structures can become damaged.
Congenital hyperinsulinism (CHI) is a condition treated at Great Ormond Street Hospital (GOSH) which causes the production of high levels of insulin. If your child has CHI, this can cause their blood glucose level to drop too low (hypoglycaemia).
Transient hyogammaglobulinaemia of infancy (THI) is the name for a condition in which the immune system matures more slowly than usual, but eventually functions entirely normally. This information sheet from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of transient hypogammaglobulinaemia of infancy (THI) and where to get help.
The brain uses a tremendous amount of oxygen in order to function. When the amount of oxygen that is available to the brain is reduced, we know that a vulnerable memory structure, called the hippocampus, can become damaged.
Septo-optic dysplasia is the name given to the condition where a child is diagnosed with two or more of the following problems: optic nerve hypoplasia, midline brain abnormalities and pituitary gland abnormalities. It is a rare condition affecting around 1 in every 10,000 births, with boys and girls affected equally.
Dr Khalid Hussain ia an Honorary Consultant in Paediatric Endocrinology at Great Ormond Street Hospital and Reader in Paediatric Endocrinology at University College London (UCL) Institute of Child Health.
Find out more about cortisol deficiency and how it is treated. This page also contains information from Great Ormond Street Hospital (GOSH) about how to deal with illnesses, accidents and other stressful events in children on cortisol replacement.
Clinical guideline from Great Ormond Street Hospital for the recognition, prevention and treatment of the refeeding syndrome in children and young people admitted in the Department of Child and Adolescent Mental Health who have experienced recent starvation.
The ketogenic diet (KD) is a therapeutic diet, which has been shown to improve seizure control in patients with drug resistant epilepsy, and is used in some patients with metabolic conditions for example, glucose transporter type 1 deficiency syndrome (GLUT1) and pyruvate dehydrogenase deficiency (PDH).
Lanreotide is used to treat persistently low blood sugar levels (hypoglycaemia) caused by the body producing too much insulin (hyperinsulinism). This information from Great Ormond Street Hospital (GOSH) describes lanreotide injections, how they are given and some of its side effects.
A haemangioma is a collection of small blood vessels that occur under the skin. They are sometimes called 'strawberry marks' because the surface of a haemangioma looks a bit like a strawberry. Applying timolol to the skin surface is one option for treating very small haemangiomas.
The purpose of this guideline is to support the safe and effective use of insulin at Great Ormond Street Hospital (GOSH). It follows the implementation of the National Patient Safety Agency (NPSA 2010) guidance “Safer Administration of Insulin” and supports best practice throughout the Trust.
Dr T-Y Hsia is a Consultant Cardiothoracic Surgeon. He has worked at Great Ormond Street Hospital for five years and is currently surgical lead for the heart transplantation and mechanical assist program. He also leads the Grown Up Congenital Heart Surgery service at Barts Hospital.
The purpose of this clinical guideline is to support staff with the recognition, prevention and treatment of refeeding syndrome in children and young people who have experienced a period of insufficient nutrition.