The brain uses a tremendous amount of oxygen in order to function. When the amount of oxygen that is available to the brain is temporarily reduced, we know that vulnerable brain structures can become damaged.
Congenital hyperinsulinism (CHI) is a condition treated at Great Ormond Street Hospital (GOSH) which causes the production of high levels of insulin. If your child has CHI, this can cause their blood glucose level to drop too low (hypoglycaemia).
Transient hyogammaglobulinaemia of infancy (THI) is the name for a condition in which the immune system matures more slowly than usual, but eventually functions entirely normally. This information sheet from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of transient hypogammaglobulinaemia of infancy (THI) and where to get help.
The brain uses a tremendous amount of oxygen in order to function. When the amount of oxygen that is available to the brain is reduced, we know that a vulnerable memory structure, called the hippocampus, can become damaged.
A discovery about an area of the brain crucial to storing memories could help children with developmental amnesia, according to a team from the UCL Institute of Child Health and Great Ormond Street Hospital (GOSH).
Septo-optic dysplasia is the name given to the condition where a child is diagnosed with two or more of the following problems: optic nerve hypoplasia, midline brain abnormalities and pituitary gland abnormalities. It is a rare condition affecting around 1 in every 10,000 births, with boys and girls affected equally.
A haemangioma is a collection of small blood vessels that occur under the skin. They are sometimes called 'strawberry marks' because the surface of a haemangioma looks a bit like a strawberry. Applying timolol to the skin surface is one option for treating very small haemangiomas.
Find out more about cortisol deficiency and how it is treated. This page also contains information from Great Ormond Street Hospital (GOSH) about how to deal with illnesses, accidents and other stressful events in children on cortisol replacement.
Lanreotide is used to treat persistently low blood sugar levels (hypoglycaemia) caused by the body producing too much insulin (hyperinsulinism). This information from Great Ormond Street Hospital (GOSH) describes lanreotide injections, how they are given and some of its side effects.
Dr Khalid Hussain ia an Honorary Consultant in Paediatric Endocrinology at Great Ormond Street Hospital and Reader in Paediatric Endocrinology at University College London (UCL) Institute of Child Health.
This guideline is to provide guidance on the administration of oxygen therapy in a non-emergency situation at Great Ormond Street Hospital (GOSH).
NOTE: We review our guidelines regularly and this guideline is now past its review date. The content of the guideline below may not reflect the most recent evidence based practice. Please use with caution.
The ketogenic diet (KD) is a therapeutic diet, which has been shown to improve seizure control in patients with drug resistant epilepsy, and is used in some patients with metabolic conditions for example, glucose transporter type 1 deficiency syndrome (GLUT1) and pyruvate dehydrogenase deficiency (PDH).
A blood glucose test is a fairly common procedure that's carried out regularly in hospitals, like Great Ormond Street Hospital (GOSH), and clinics. The test is to find out how much glucose (sugar) you have in your blood.
A haemangioma is a collection of small blood vessels that occur under the skin, sometimes called ‘strawberry marks’. Similar collections of blood vessels can occur in the air passage beneath the vocal cords. These are called "subglottic haemangiomas". Children with subglottic haemangioma will usually have noisy breathing but normal cry.