Methotrexate is a chemotherapy drug that is used to treat certain types of cancer and leukaemia. This page from Great Ormond Street Hospital (GOSH) explains what intravenous methotrexate is, how it is given and some of the possible side effects.
Methotrexate is a medicine that has been used to treat chronic inflammatory conditions such as juvenile idiopathic arthritis, juvenile dermatomyositis, systemic lupus erythematosus, vasculitis and severe psoriasis for many years.This information sheet from Great Ormond Street Hospital (GOSH) explains about the use of methotrexate in such conditions.
Rituximab (brand name MabThera®) is a relatively new medicine which works on the immune system. It removes some of the white blood cells in the body which are called B cells. Removing these stops the production of antibodies that may play a role in your child’s illness.
This page explains about polyarteritis nodosa (PAN), what causes it and how it can be treated. It also gives details of what to expect when your child comes to Great Ormond Street Hospital (GOSH) for assessment and treatment.
Parry-Romburg syndrome (also known as Progressive Hemifacial Atrophy) is a rare condition affecting the skin and soft tissues on one side of the face (hemifacial). This information sheet from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of Parry-Romburg syndrome and where to get help.