Immunoglobulin is also known as IgG or antibody. It is a blood product and is given often as replacement for people who are unable to make their own antibodies. This information sheet from Great Ormond Street Hospital (GOSH) explains what immunoglobulin is, why it is used in Neurology, how it is given and some of the possible side effects.
PICU (Seahorse), NICU (Dolphin) and CICU (Flamingo) are units for babies, children and young people requiring intensive care. This page explains a little about the Paediatric Intensive Care Unit (PICU), Neonatal Intensive Care Unit (NICU) and Cardiac Intensive Care (CICU) at Great Ormond Street Hospital (GOSH). We hope that this will help you at this difficult time.
We all have medicines of some kind at home, some of which could be dangerous if taken incorrectly. Here Great Ormond Street Hospital (GOSH) explains how to keep your medicines safe at home. You'll also find tips for keeping a well-stocked but safe medicine cabinet.
Anti-TNF medicines, such as adalimumab, etanercept and infliximab, act against a protein in the blood called Tissue Necrosis Factor Alpha (TNFα). This protein can cause inflammation when it is present in large amounts in the blood.
Methotrexate is a medicine that has been used to treat chronic inflammatory conditions such as juvenile idiopathic arthritis, juvenile dermatomyositis, systemic lupus erythematosus, vasculitis and severe psoriasis for many years.This information sheet from Great Ormond Street Hospital (GOSH) explains about the use of methotrexate in such conditions.
Steroids are hormonal substances that are produced naturally in the body by the adrenal glands (which are just above each kidney) and by the reproductive organs. There are many different types of steroids and they have different effects on the body.
This guideline is intended to guide and facilitate the care of patients under the care of the clinical teams at Great Ormond Street Hospital for Children NHS Trust (GOSH). It has been approved by the Guideline Approval Group and is for use by staff of all disciplines and levels in these health care teams. The guidance contained here in is not intended to replace individual assessment and personalised treatment of the patient.
NOTE: We review our guidelines regularly and this guideline is now past its review date. The content of the guideline below may not reflect the most recent evidence based practice. Please use with caution.
The skin is complex with an array of functions. It is the body’s largest organ, protecting the deeper tissues and organs from mechanical damage, chemical damage, bacterial damage, ultraviolet radiation and thermal damage. The skin aids in regulating body temperature, in excretion of urea and uric acid and also synthesis of vitamin D (Marieb 2012).