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Neuronal migration disorder

Neuronal migration disorder is an umbrella term given to several conditions including lissencephaly, agenesis of the corpus callosum and microgyria. They all arise while the baby is developing in the womb.This information sheet from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of neuronal migration disorders and where to get help.

Neuromyelitis optica spectrum disorder

Neuromyelitis optica spectrum disorder (NMOSD) is a rare neurological (brain) condition characterised by episodes of optic neuritis (inflammation or swelling of the optic nerve), transverse myelitis (inflammation or swelling of the spinal cord), together with one or more other diagnostic criteria including in some cases the presence of a specific antibody (AQP4).This information sheet from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of neuromyelitis optica spectrum disorder (NMOSD) and where to get help.

Open tip rhinoplasty for children with craniofacial disorders

A rhinoplasty is an operation to reshape the bone and cartilage in the nose. An open tip rhinoplasty is one where incisions are made to access inside the nostrils. This information sheet from Great Ormond Street Hospital (GOSH) explains the open tip rhinoplasty operation for children with craniofacial disorders. It explains how to prepare your child for surgery as well as what to expect in hospital afterwards.

Isotretinoin

Isotretinoin is a retinoid, which is a type of Vitamin A. It is commonly used for the treatment of severe acne. This information sheet from Great Ormond Street Hospital (GOSH) explains what isotretinoin acid is, how it is given and some of the possible side effects.

Surgery for epilepsy

Great Ormond Street Hospital (GOSH) has had a programme for surgery for treating epilepsy in children since 1992. GOSH has the facilities needed for the investigations, tests and treatment your child may need. These facilities are specifically for children and the specialists who use them have many years’ experience of children with epilepsy.

Adalimumab injections

Anti-TNF medicines, such as adalimumab, etanercept and infliximab, act against a protein in the blood called Tissue Necrosis Factor Alpha (TNFα). This protein can cause inflammation when it is present in large amounts in the blood.

Spinal surgery at GOSH

At Great Ormond Street Hospital (GOSH), we have developed a pathway for children and young people having spinal surgery. Spinal surgery is a complex procedure, so we want you to understand the benefits and risks of the operation so you can make an informed decision about whether to go ahead. This page explains what will happen from your child’s initial clinic appointment through to discharge, which clinicians you may meet and what to expect.

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