NIHR Great Ormond Street Hospital BRC

A collaboration between Great Ormond Street Hospital and the UCL Great Ormond Street Institute of Child Health

Latest BRC news

Read about our latest research below or visit our news page to learn more about our projects.

Researchers announce oesophagus regeneration trial

A team led by Professor Paolo De Coppi has announced that they are set to build and transplant an oesophagus using organs harvested from pigs and then modified using a child’s stem cells. The organs will be created for children who are born with a severe cases of oesophageal atresia, where their oesophagus has not formed properly. 

Researchers awarded up to £1 million to develop gene therapy for serious immunodeficiency

The UCL Technology Fund (UCLTF) has approved an investment of up to £1 million to support researchers Professor Adrian Thrasher, Professor Bobby Gaspar, and Dr GiorgiaSantilli in developing a gene therapy approach for treating p47phox-deficient chronic granulomatous disease (p47-CGD).

Tissue removed during heart surgery is saving lives of children with no immune system

In a European first, a little-known gland called the ‘thymus’, some of which is routinely removed during cardiac surgery, has saved the lives of children with a life threatening immunodeficiency condition, complete DiGeorge syndrome (cDGS).