NIHR Great Ormond Street Hospital BRC

A collaboration between Great Ormond Street Hospital and the UCL Great Ormond Street Institute of Child Health

Latest BRC news

Read about our latest research below or visit our news page to learn more about our projects.

Low myostatin levels linked to lack of success of anti-myostatin drugs for muscle-wasting conditions

Levels of myostatin, a protein that prevents muscle growth, could influence how well the body responds to anti-myostatin treatments for muscle-wasting conditions such as Duchenne Muscular Dystrophy (DMD). This breakthrough could help predict which patients will benefit from therapies that aim to increase muscle strength by blocking myostatin.

Advances in the treatment of the severe immune disorder Wiskott-Aldrich syndrome

Researchers at Great Ormond Street Hospital (GOSH) have made an important breakthrough in understanding how the immune system becomes disrupted in Wiskott-Aldrich syndrome (WAS), a genetic disorder where the patient’s immune cells begin attacking their own body.