[Skip to content]

.

Neuroblastoma research grant

20 August 2008

We're pleased to confirm a grant from the Neuroblastoma Society to Dr Arturo Sala, University College of London Institute of Child Health.

(£164,000): Re-activating ApoJ/clusterin expression as a novel therapeutic approach for neuroblastoma. This study takes aims to propose to understand the precise mechanism by which MYCN (a gene implicated in aggressive neuroblastoma) downregulates the ApoJ/clusterin gene, and whether reactivating ApoJ/clusterin inhibits neuroblastoma development.

These so-called "epigenetic" drugs are already approved for use in adults so success with the project could pave the way to their use for children with aggressive neuroblastomas."

DR Sala said "I'm grateful to the Neuroblastoma Society for backing this important work.  Aggressive neuroblastoma can be one of the most difficult cancers to treat in children and new therapeutic approaches are needed."

Contact information:

GOSH-ICH Press Office: 020 7239 3125
Email: Coxs@gosh.nhs.uk
For genuine and urgent out of hours call speak to switchboard on 020 7405 9200

Notes to editors

Great Ormond Street Hospital for Children NHS Trust is the country’s leading centre for treating sick children, with the widest range of specialists under one roof.

With the UCL Institute of Child Health, we are the largest centre for paediatric research outside the US and play a key role in training children’s health specialists for the future.

Our charity needs to raise £50 million every year to help rebuild and refurbish Great Ormond Street Hospital, buy vital equipment and fund pioneering research. With your help we provide world class care to our very ill children and their families.

Recent press releases