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ICH study reveals pain may be ‘linked with low vitamin D’

13 August 2008

A study led by Dr Elina Hyppönen at ICH has shown that low levels of the sunshine vitamin, vitamin D, may contribute to chronic pain among women.

The link does not apply to men, suggesting hormones may be involved, according to the study which was published this week in the Annals of Rheumatic Diseases.  The team from ICH said studies were now needed to see if vitamin D supplements can guard against chronic pain.

About one in 10 people are affected by chronic pain at any one time in the UK. The causes are not well understood and much of the focus to date has been on emotional factors.

Among the 7,000 men and women aged 45 from across England, Scotland and Wales who were involved in the study, those who were smokers, non-drinkers, overweight and underweight all reported higher rates of chronic pain. Among the women, vitamin D levels also appeared to be important.

This finding was not explained by gender differences in lifestyle or social factors, such as levels of physical activity and time spent outdoors, say the research team. Women with vitamin D levels between 75 and 99 mmol/litre - a level deemed necessary for bone health - had the lowest rates of this type of pain, at just over eight per cent.

Women with levels of less than 25 mmol/litre had the highest rates, at 14.4%. Severe lack of vitamin D in adults can lead to the painful bone disease osteomalacia but the team said osteomalacia did not account for their findings.

Dr Hyppönen said: “Further work is now needed to evaluate whether vitamin D supplements can help prevent chronic pain.  If I had chronic pain, I would certainly check I was getting enough vitamin D. That said, our earlier work has shown that the problem with hypovitaminosis D is very common in northern latitudes, such as the UK, especially during winter and spring. Now that the sunny season is about to end, and given the suggested influences of vitamin D deficiency on other diseases including cancer, cardiovascular disease and diabetes, ensuring adequate levels of vitamin D intake would be beneficial for most of us."

For further information on hypovitaminosis D please visit: http://www.ich.ucl.ac.uk/pressoffice/pressrelease_00510

Contact information:

Hayley Dodman, GOSH-ICH press office: 020 7239 3126
Email: dodmah@gosh.nhs.uk
For genuine and urgent out of hours call speak to switchboard on 020 7405 9200

Notes to editors

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