A type of brain surgery conducted in childhood for medication-resistant epilepsy not only reduces chronic seizures but can protect memory development, a study by a team from Great Ormond Street Hospital (GOSH) and its research partner the UCL Institute of Child Health (ICH) has found.
A genetic discovery by a team from the UCL Institute of Child Health and Great Ormond Street Hospital could lead to new therapies to tackle neurological degeneration and resulting loss of motor skills seen in a diverse group of central nervous system disorders.
Changes in the way working genes are delivered to children with SCID (Severe Combined Immunodeficiency) could make gene therapy for the disease even safer, finds research led by a team at Great Ormond Street Hospital (GOSH) and its research partner the UCL Institute of Child Health
Newborn immune T-cells – specialist cells that help to defend the body against infection – may have the ability to trigger an inflammatory response to bacteria, something that we didn't previously think was possible, finds a study led by King’s College London and involving teams at Great Ormond Street Hospital (GOSH).
GOSH patients, families, doctors and nurses have played a major role in the build up to a national project that hopes to analyse the DNA of tens of thousands of people with rare diseases and cancers in order to better understand, and ultimately treat, rare genetic conditions.