In the womb, the retina (the light sensitive surface at the back of the eye that converts images into nerve signals that the brain understands) develops slowly and the retinal blood vessels often only complete growing by the end of gestation. If a child is born prematurely these blood vessels can grow abnormally causing damage to the retina and of course vision. This is called retinopathy of prematurity.
Saethre-Chotzen syndrome is a type of complex craniosynostosis named after the two doctors who described it in the mid-20th century. This page from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of Saethre-Chotzen syndrome and where to get help.
Sagittal craniosynostosis is the most common type of non-syndromic craniosynostosis and occurs when the sagittal suture fuses before birth. This page from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of sagittal craniosynostosis (also known as scaphocephaly) and where to get help.
Selective mutism is a childhood anxiety disorder where a child cannot speak in almost all social situations despite being able to. Selective mutism usually begins in children under five years of age, though it may only become noticeable when a child begins school. Most children with selective mutism are believed to have an inherited predisposition to anxiety and there can be a variety of additional contributing causes.
Septicaemia is another term used to describe blood poisoning. It is an infection caused by large amounts of bacteria entering the bloodstream. It is a potentially life-threatening infection that affects thousands of patients every year.
Septo-optic dysplasia is the name given to the condition where a child is diagnosed with two or more of the following problems: optic nerve hypoplasia, midline brain abnormalities and pituitary gland abnormalities. It is a rare condition affecting around 1 in every 10,000 births, with boys and girls affected equally.
This booklet has been produced jointly between PID UK, Great Ormond Street Hospital (GOSH) and the Great North Children’s Hospital. The information has been reviewed by the PID UK Medical Advisory Panel and Patient Representative Panel and by families affected by PID. It is designed to help answer the questions families may have about the immune condition called severe combined immunodeficiency (SCID) but should not replace advice from a clinical immunologist.