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Epidermolysis bullosa simplex: generalised severe type 

Epidermolysis bullosa (EB) is the term used to describe a number of rare genetic conditions which cause the skin to blister and shear in response to minimal friction and trauma. There are four broad categories of EB: EB simplex, junctional EB, dystrophic EB and Kindler syndrome. Within each of these categories there are several subtypes. One of the subtypes of EB simplex is the generalised severe type (previously known as Dowling Meara type).


Epilepsy is a type of brain disorder treated at Great Ormond Street Hospital (GOSH) where your brain 'short circuits' so the electrical messages travelling to and from the brain are disrupted.


Exomphalos is a type of abdominal wall defect. It occurs when a child’s abdomen does not develop fully while in the womb. This page explains about exomphalos or omphalocele, what causes it and what to expect when your child comes to Great Ormond Street Hospital (GOSH) for treatment.

Febrile convulsions

Febrile convulsions are a type of fit (seizure) that can happen when a child, usually between the ages of six months and five years, has a high temperature. One in 50 children will have had a febrile convulsion by the time they are five years old. Therefore it is a very common illness, which children usually outgrow without any lasting effects.

Fibrous dysplasia

Fibrous dysplasia is a congenital (present at birth) condition that affects bone growth and development. Instead of maturing into solid bone, affected bones stay at the immature fibrous stage so are weak and misshapen.This page from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of fibrous dysplasia and where to get help.

Food allergies

If you have a food allergy, you might not be able to eat certain things in case they cause an allergic reaction. Your body's immune system will react to a substance that is usually harmless, resulting in a number of chemicals being released into your bloodstream.

Food allergy

Food allergy is a type of food hypersensitivity where the body’s immune system has a reaction to a substance that is usually harmless, resulting in the release of a number of chemicals into the bloodstream. Common foods causing an allergy in children include: cow’s milk, eggs, shellfish and peanuts. Substances that cause an allergic reaction are called allergens.