Medicines information

The information in this section describes medicines, how they are given and some of their possible side effects.

If you have any questions or concerns about medications, please ask your doctor, nurse or pharmacist.

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Pancreatic enzyme replacement in congenital hyperinsulinism

Digestive enzymes are made in the pancreas. The fat, protein and carbohydrate in food is broken down by the enzymes to release nutrients. „„In congenital hyperinsulinism (CHI), if surgery has removed all or part of the pancreas, the food cannot be digested and absorbed by the body. This is called malabsorption and causes loose or oily stools, wind, stomach ache and poor weight gain.

Potassium iodate 

Potassium iodate is a thyroid blocking medicine. It is given before a particular type of isotope scan at Great Ormond Street Hospital (GOSH) called a MIBG scan. The potassium iodate protects the thyroid against the isotope given during this scan.

Procarbazine

Procarbazine is a chemotherapy medicine used to treat cancer, such as Hodgkin’s Disease, a cancer of the lymph glands. It is occasionally used to treat liver and brain tumours.

Propranolol for headaches

Propranolol belongs to a group of drugs called beta blockers. It is used in patients with heart problems to control high blood pressure or irregular heart beats. It is also used to treat certain types of vascular birthmarks. It is also used to prevent migraines and headaches.

Rasburicase

Rasburicase is a medicine that is sometimes given at the start of chemotherapy for leukaemia or lymphomas. When chemotherapy starts to kill the leukaemia or lymphoma cells, uric acid is released from inside these cells. It can crystallise and cause damage to the kidneys. Rasburicase works by allowing uric acid to be more easily removed from the body by the kidneys.