Ubiquinone 30mg in 5ml oral solution 

Ubiquinone is also known as coenzyme Q10 or ubiquinone. It is found naturally in many foods, such as meat and fish, and helps cells to generate energy. Ubiquinone has been used for heart problems such as heart failure, angina or high blood pressure. It may also prevent damage to the heart caused by certain medicines. Other uses include cancer treatment, muscle problems and metabolic diseases.

Ubiquinone as an oral liquid preparation is not readily available from your community pharmacy. It is not available in the UK so has to be imported from abroad by a licensed pharmaceutical import company. Supplies of this medicine may take longer than usual to obtain, usually several days, but in some cases, a couple of weeks. If agreed, your family doctor (GP) and community pharmacist can obtain the medicine from a licensed pharmaceutical import company.

How is it given?

Ubiquinone is given by mouth (orally), once or twice a day with food. It is available as an oral solution, which contains 30mg of active ingredient in 5ml of liquid. This means that the strength of the oral solution is 30mg/5ml. Always check that you are giving your child the correct strength of medicine.

Ubiquinone is also available in tablet or capsule form.

Who should not use ubiquinone?

People with the following conditions should discuss using ubiquinone with their doctor.

  • „„Hypersensitivity to ubiquinone or any of its ingredients.
  • „„Pregnant, could be pregnant, trying to become pregnant or breastfeeding.
  • „„Lactose insufficiency, galactosaemia or glucose/galactose malabsorption syndrome, hereditary fructose intolerance.
  • „„Type 1 diabetes (insulin dependent).
  • „„Existing liver problems. 

What are the side effects of ubiquinone?

If any of these side effects are severe or carry on for a long time, please tell your doctor.

  • „„upset stomach, nausea, diarrhoea and/or indigestion
  • „„headache or dizziness
  • „„irritability or agitation
  • „„sleep problems 

Ubiquinone and other medicines

Some medicines can react with ubiquinone, altering how well it works. Always check with your doctor or pharmacist before giving your child any other medicine, including medicines on prescription from your family doctor (GP), medicines bought from a pharmacy (chemist) or any herbal or complementary medicines.

  • „„warfarin and other anti-coagulant medicines
  • „„insulin
  • „„anti-cholesterol medicines
  • „„beta-blockers 

Important information

  • „„Keep medicines in a safe place where children cannot reach them.
  • „„The oral solution should be kept in its original packaging in a cool, dry place away from direct sunlight and heat.
  • „„As ubiquinone oral solution has to be imported from abroad, it can take longer to supply than other medicines. Always remember to ask your doctor for a repeat prescription in plenty of time.
  • „„If you forget to give your child a dose and it is within a few hours of when the dose was due, give it as soon as you remember. Otherwise, do not give this dose but give the next dose when it is due. Do not give a double dose.
  • „„If your child vomits straight after taking the dose, inform your local doctor or nurse, as your child may need to take another one.
  • „„If your doctor decides to stop treatment or thesolution passes its expiry date, return any unused solution to the pharmacist. Do not flush it down the toilet or throw it away.
Compiled by: 
The Pharmacy Department in collaboration with the Child and Family Information Group This information does not constitute health or medical advice and will not necessarily reflect treatment at other hospitals.
Last review date: 
April 2014
Ref: 
2014F1013

Disclaimer

Please read this information sheet from GOSH alongside the patient information leaflet (PIL) provided by the manufacturer. If you do not have a copy of the manufacturer’s patient information leaflet please talk to your pharmacist. A few products do not have a marketing authorisation (licence) as a medicine and therefore there is no PIL.

For children in particular, there may be conflicts of information between the manufacturer’s patient information leaflet (PIL) and guidance provided by GOSH and other healthcare providers. For example, some manufacturers may recommend, in the patient information leaflet, that a medicine is not given to children aged under 12 years. In most cases, this is because the manufacturer will recruit adults to clinical trials in the first instance and therefore the initial marketing authorisation (licence) only covers adults and older children.  

For new medicines, the manufacturer then has to recruit children and newborns into trials (unless the medicine is not going to be used in children and newborns) and subsequently amend the PIL with the approved information. Older medicines may have been used effectively for many years in children without problems but the manufacturer has not been required to collect data and amend the licence. This does not mean that it is unsafe for children and young people to be prescribed such a medicine ‘off-licence/off-label’. However, if you are concerned about any conflicts of information, please discuss with your doctor, nurse or pharmacist.