About the Gastroenterology department

The Gastroenterology department at Great Ormond Street Hospital is one of the UK’s leading centres of excellence in treating complex diseases affecting the gut and other associated organs (such as the pancreas).  
Staff on Kingfisher Ward

The Gastroenterology department of Great Ormond Street Hospital is well recognised as a leading centre of advanced paediatric gastrointestinal medicine, clinical research and teaching. The department provides integrated clinical and academic activity between Great Ormond Street Hospital and the University College London (UCL) Institute of Child Health. The aim of the department is to provide a high standard of care for children with complex gastroenterological diseases. The department is committed to translating excellence in research and teaching into the provision of high quality patient-focussed medical and nursing care, and to further understanding of the cause, development and treatment of gastro-intestinal (GI) disorders in children.

Due to its specialisation, the department offers a sub-specialist referral service to gastroenterologists throughout the UK and worldwide. 

Key strengths:

  • a proven track record of translating basic science into clinical therapies to combat diseases

  • the UK’s only gut tissue engineering facility

  • recognised academic success in research and development

  • unique potential to meet new challenge areas in treating gut disease and food allergies

  • the largest group of paediatric home parenteral nutrition (PN) patients in the UK

  • Links with Kings College for small bowel transplant assessment

Gastroenterology investigations suite wide shot
Gastroenterology investigations suite


The following sub-specialty areas within paediatric gastroenterology have been developed by the Gastroenterology department:

  • Neurogastroenterology and motility - where either one or both of the bowel nerves and muscles do not work properly (eg: pseudo-obstruction)

  • Mucosal immunology - where diseases and conditions driven by the immune system cause inflammation and affect the bowel’s ability to work effectively (eg: inflammatory bowel disease, allergies, coeliac disease)

  • Intestinal rehabilitation - where significant portions of the bowel are unable to function, resulting in malabsorption that requires rehabilitation and often the use of artificial nutrition called total parenteral nutrition

The department has close links to Paediatric Surgery department, and to the Dietetic and Pharmacy departments, which provide Nutritional Support Services for the hospital. The strong links to the Immunology and Bone Marrow Transplant Units have expanded further with the aim to develop joint weekly meetings and regular joint clinics.

The clinical department is intimately associated with the academic department within the Institute of Child Health where there is an active research programme into aspects of intestinal adaptation and secretion, Intestinal inflammation, pancreatic disease and enteric neuromuscular disease.